language: Thai English

ເທັກໂນໂລຢີບາດແຜໜ້ອຍສຸດລະດັບສາກົນ + ຜູ້ຊ່ຽວຊານດ້ານມະເຮັງ, ການໃຫ້ຄຳປຶກສາດ້ານມະເຮັງ 1v1 ເວລາ: ວັນທີ 22 ມີນາ 2025 (ວັນເສົາ) ເວລາ 9:00-12:00 ໂມງ
Line
Customer Service
Back to Top

Gene Targeted Therapy

Applicable diseases:  Lung cancer, breast cancer, gastric cancer, non-Hodgkin's lymphoma, etc.

Technology advantages:  Precise targeting of tumor site, long drug effect time, high lethality without damaging normal tissues

Reserve

1744016761168.jpg



1. Cancer: a molecular network disease


An important feature of malignant tumor cells is that due to the instability of their genome, new mutant cells are constantly generated during the continuation of cell division, and a population of mutant cells with different biological characteristics appears in tumor cells. Mutant genes in tumors are not only numerous and functionally complex, but also in a dynamic biological network. 


In the cell, interconnected genes/proteins form a complex cellular network, including signaling pathways, gene regulatory networks and metabolic networks. Mutated genes have different positions in the cellular network and may have different impacts on the network, and different network structures have different tolerances to mutations. In this sense, tumor is actually a molecular network disease, and the degree of abnormality and complexity of the molecular network determines the malignant phenotype of the tumor and individual differences.


2. Mechanism

Gene-targeted therapy is to design corresponding therapeutic drugs for the cancer-causing site that has been clearly identified (the site can be a protein molecule inside the tumor cell or a gene fragment), and the drugs will enter the body to specifically select the cancer-causing site to combine with the action, so as to make the tumor cells die specifically without affecting the normal tissue cells around the tumor, in simple words, it is a method to find the tumor target - a certain gene, and then eliminate it. In short, this is a method to find the tumor target - a certain gene, and then eliminate it.


Gene-targeted therapy aims at the root cause of the disease - the abnormal gene itself, and is the "cure" therapy for cancer.

Cancer is a group of diseases in which the body's normal self-regulatory mechanisms no longer control the growth of some kinds of cells. Cells are frequently exposed to a variety of agents, from both external and internal sources, which damage DNA. Even minor DNA damage can have profound effects, causing certain genes to become overactive, to undergo partial or complete inactivation, or to function abnormally. Genes control a number of protective pathways in cells that prevent cells from becoming cancerous. 


For example, pathways that transmit signals for a cell to divide have on-off switches to control cell division. Cells also have mechanisms that allow them to determine if their DNA has been damaged, and they have pathways to repair that damage or eliminate the cell. The failure of any of these protective pathways can lead to the development of cancer.


3. Gene targeted therapy VS surgery & chemoradiotherapy


*Gene targeted therapy: Targeting key cancer-causing sites (e.g., enzymes, proteins, receptors, etc.) in the growth of cancer cells and "launching missiles" to kill the growth of cancer cells specifically.


*Surgery: Traumatic and easy to recur and cause complication


*Traditional chemotherapy and radiotherapy: Toxic treatment, high toxicity and side effects, kills both bad cancer cells and normal cells


4. Process of gene-targeted therapy

(1)Acquisition of therapeutic genes
(2)Selection of gene carriers
(3)Selection of target cells
(4)Gene transfer method
(5)Selection and identification of transduced cells
(6)Retransfusion in the body


5. Advantages


(1)Make the drug aim at the tumor site, with high targeting;.
(2)Preserve relatively high drug concentration locally.
(3) Prolonging the time of drug action.
(4) Improve the killing power of tumor cells.
(5)No damage to normal tissues, reducing patients' pain and complications.
(6)Non-cytotoxic, effective, low toxicity, high tolerance.
(7)It can be used alone or in combination, and has better effect when combined with conventional treatment (chemotherapy and radiotherapy).


Patient Stories

Minimally invasive interventional therapy helped me survive for more than 8 years with stage IV cervical cancer* Cervical cancer
Fei Fei
Indonesia
Treatment programs: Interventional Therapy
Description: "I believe in God and be grateful for everything, even cancer. Since this is a necessary trial in my life, I choose to be optimistic. I have cancer, but cancer has not defeated me." Fei Fei in treatment There will inevitably be setbacks in life In October 2016, I was diagnosed with stage ⅠB cervical cancer during a random physical examination. I normally enjoy exercise and have a regular daily routine, but I had "won the lottery" so I was unprepared for the unexpected news, and I was upset and scared, but I still believed that there was a way out. local doctor advised me to have immediate surgery to prevent my condition from getting worse, but I had already signed up for the Cuban marathon at the time and decided to wait until after the race was over. After the competition I was checked again in a hospital in Singapore, the result showed 4B cervical cancer and the advice given by the doctors was chemotherapy, considering that the side effects of chemotherapy would affect my quality of
more >
How to find the way of rebirth for postoperative metastasis of cervical cancer? Cervical cancer
Wei Ji
Indonesia
Treatment programs: Interventional therapy + Natural therapy
Description: In May 2023, Wei Ji (pseudonym), who had stage III cervical cancer, relapsed one month after surgery and came to our hospital (St. Stamford Modern Cancer Hospital Guangzhou) to seek better treatment methods, hoping to improve treatment hope.
more >
Cervical cancer stage IIIB recurrence, minimally invasive interventional therapy strikes deep into the lesion to kill cancer cells Cervical cancer
Edoharidwi Doko
Indonesia
Treatment programs: Interventional therapy + Natural therapy
Description: Edoharidwi Doko from Surabaya, Indonesia, was diagnosed with stage IIIB cervical cancer in 2022. After undergoing radiotherapy and chemotherapy, the cancer recurred and metastasized to the abdominal cavity. Following minimally invasive treatment at St. Stamford Modern Cancer Hospital Guangzhou, her physical discomfort has significantly decreased, the abdominal tumor has disappeared, and her quality of life has improved.
more >
Precision Minimally Invasive Treatment Eradicates 2.9cm Tumor for Cervical Cancer Patient Cervical cancer
Diana Kartika Arma
Indonesia
Treatment programs:
Description: Diana Kartika Arma, 57, from Jakarta, Indonesia, suffered abnormal vaginal bleeding in November 2021. After examination, she was diagnosed with stage IB2 of cervical cancer and her weight lost 8kg. In October 2024, the 1.5x1.2x2.9 cm tumor and vaginal bleeding symptoms "completely disappeared" after treatment. Currently, her sleep, appetite, weight and life quality have been improved.
more >
Appointment Form close
Please fill in your information and we will contact you as soon as possible.
ติดต่อทันที