Radioactive Particle and Chemical Particle Combined Implantation
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Applicable diseases: Increase the cumulative dose in the tumor and reduce the measures in the surrounding important organs, so that the cancer cells of different division cycles can be irradiated. Play the role of sensiti
Technology advantages: Increase the cumulative dose in the tumor and reduce the measures in the surrounding important organs, so that the cancer cells of different division cycles can be irradiated. Play the role of sensiti
Video of Radioactive Particle and Chemical Particle Combined Implantation
What is Radioactive Particle and Chemical Particle Combined Implantation?
Under the guidance of CT or B-mode Ultrasound, radioactive particle and chemical particle will be implanted into the tumor in turn so that it can realize the synchronization of radiotherapy and chemotherapy. This technology is convenient, safe, minimally invasive and low incidence of complication. It is a good therapy for cancer patients at advanced stage.
How do Radiotherapy Particle and Chemotherapy Particle Take Effects?
Modern Cancer Hospital Guangzhou applied 125I seeds as radioactive particles that can give off short-range γ-ray to kill tumor cells continuously. 125I seed implantation can achieve the same internal radiation effects as surgery does and have little complication and few side-effects. The half-life period of 125I seed is 60.1 days. As the radiological dose gradually decrease, 125I seed can effectively exposure up to 180 days in body since it is planted.
Chemical particle, also called interstitial chemotherapy, is to put anticancer medicine to load on degradable or non-degradable excipient so that they can build up a drug delivery system. The carriers are natural macromolecule material or synthetic macromolecule material. Chemical particle is implanted into tumor tissue and tumor bed, which is in interstitial substance of tumor cycle or after excision.
Research shows that if the effective anticancer medicine is implanted in a part of a solid tumor or neoplastic lesion in serosa, even nearby the normal tissue, the part of tumor will stay at high concentration of medicine, which is largely higher than the concentration of blood body circulation, in the period of medicine diffusion. It usually lasts two to fifteen days and takes effect on killing cancer cells and controlling the partial lesion.
The implanted chemical particle, as the supplement of radiotherapy, not only kills the cancer cells with high dose of medicine as the interventional therapy does, but also takes sensitization effect on radioactive particle and reinforces the efficacy of radiotherapy.
Procedures
Radioactive Particle and Chemical Particle Combined Implantation is that the radioactive particle and chemical particle will be implanted in turn by percutaneous puncture into the tumor or near the tumor. This therapy is safe and with easy procedure, small trauma and little complication.
The Advantages of Radioactive Particle and Chemical Particle Combined Implantation
1) Chemical particle diffuses in some area so that cells of a large area can get to the high-concentration chemotherapy medicine and make up the mistakes for insufficient initial dose of radiotherapy particles.
2) Chemical particle takes long effect on some parts and has high-concentration impulse therapy to tumor tissue. Also, it can maintain effective concentration for a long time and restrain invasion and metastasis of small cancer cells. Chemical particle through lymph flows to lesion so that it can effectively prevent metastasis of lymph.
3) Radioactive particle and chemical particle take dual effects on anticancer and increase the control rate of tumor.
4) The jointed application of radioactive particle and chemical particle makes chemotherapy medicine take sensitization effect of radiotherapy and strengthen the anticancer efficacy.
5) Though chemical particle, as well as the radioactive particle, generates high-concentration medicine partially, there are a small amount of them that can get into the blood circulation and at slow speed so comparing to the same dose of general chemotherapy, the side-effect of chemical particle is in lower rate and lower degree.
6) Radioactive particle and chemical particle are implanted at the same time so that it can take one surgery and get dual effects without extra surgery procedure.
Indication
Radioactive Particle and Chemical Particle Combined Implantation is used to treat many kinds of primary cancers and cancer metastasis, such as head-neck cancer, breast cancer, prostate cancer, lung cancer, liver cancer, kidney cancer, cervical cancer and other solid tumor. This technology gets good efficacy.
The Number of Particle
The number of particle depends on the sizes of cancer lesion. The bigger the tumor it is, the more particles of radiotherapy and chemotherapy it need. During review check, if there are not enough particles, patients need to be implanted more.
Patient Stories
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Cervical cancer
- Fei Fei
- Indonesia
- Treatment programs: Interventional Therapy
- Description: "I believe in God and be grateful for everything, even cancer. Since this is a necessary trial in my life, I choose to be optimistic. I have cancer, but cancer has not defeated me." Fei Fei in treatment There will inevitably be setbacks in life In October 2016, I was diagnosed with stage ⅠB cervical cancer during a random physical examination. I normally enjoy exercise and have a regular daily routine, but I had "won the lottery" so I was unprepared for the unexpected news, and I was upset and scared, but I still believed that there was a way out. local doctor advised me to have immediate surgery to prevent my condition from getting worse, but I had already signed up for the Cuban marathon at the time and decided to wait until after the race was over. After the competition I was checked again in a hospital in Singapore, the result showed 4B cervical cancer and the advice given by the doctors was chemotherapy, considering that the side effects of chemotherapy would affect my quality of
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Cervical cancer
- Wei Ji
- Indonesia
- Treatment programs: Interventional therapy + Natural therapy
- Description: In May 2023, Wei Ji (pseudonym), who had stage III cervical cancer, relapsed one month after surgery and came to our hospital (St. Stamford Modern Cancer Hospital Guangzhou) to seek better treatment methods, hoping to improve treatment hope.
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Cervical cancer
- Edoharidwi Doko
- Indonesia
- Treatment programs: Interventional therapy + Natural therapy
- Description: Edoharidwi Doko from Surabaya, Indonesia, was diagnosed with stage IIIB cervical cancer in 2022. After undergoing radiotherapy and chemotherapy, the cancer recurred and metastasized to the abdominal cavity. Following minimally invasive treatment at St. Stamford Modern Cancer Hospital Guangzhou, her physical discomfort has significantly decreased, the abdominal tumor has disappeared, and her quality of life has improved.
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Cervical cancer
- Diana Kartika Arma
- Indonesia
- Treatment programs:
- Description: Diana Kartika Arma, 57, from Jakarta, Indonesia, suffered abnormal vaginal bleeding in November 2021. After examination, she was diagnosed with stage IB2 of cervical cancer and her weight lost 8kg. In October 2024, the 1.5x1.2x2.9 cm tumor and vaginal bleeding symptoms "completely disappeared" after treatment. Currently, her sleep, appetite, weight and life quality have been improved.
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